Tioga Research continually seeks to expand its knowledge of the skin and of how formulations interact with the skin. The company has collaborated with other groups in a number of research areas, such as (i) exploring descriptor-property relationship (“DPR”) approaches to predicting skin permeation and skin irritation potential, (ii) assessing how control of solid state form modulates formulatability, (iii) optimizing percutaneous immunization, and (iv) text mining. 

Tioga Research is currently interested in expanding activities in the following areas: 

• Skin property measurements in a spatially-resolved fashion 
• Organotypic skin cultures and 3D-printed skin tissues 
• Use of nanoparticulate materials in topical formulations 
• Mesoscopic models to predict permeation pathways and cumulative flux  
• Skin and mucosal microbiome analysis, impact, and modulation 
• Mechanisms of skin immune response 
• Non-destructive ex vivo/in vitro skin imaging methods 
• In silico modeling of formulation–skin interactions that enhance or retard penetration 
• Skin barrier changes associated with disease that impact formulation-skin interactions
• Skin barrier changes associated with environmental factors e.g. UV radiation, pollution 

If you have complementary capabilities in one of these areas (or any other facet of skin biology or measurement) and would be interested to explore such a scientific collaboration, please contact us at info@tiogaresearch.com.   One of Tioga Research’s senior scientists will be pleased to be in touch with you.